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World Rare Diseases Day

February 28 marks World Rare Diseases Day. At the Paley European Institute, we stand in solidarity with all those struggling with these diseases and aim to raise public awareness of them.

Multiple cartilage and bone outgrowth syndrome (MHE)

We invite you to read a short interview with our doctors, in which they introduce you to one of the rare diseases - multiple cartilaginous outgrowth syndrome (MHE). From the interview you will learn what MHE sufferers have to deal with and what the treatment methods are.

We also encourage you to watch the episode "Fridays with Feldman , " in which prominent rare disease specialist David S. Feldman, MD, discusses the extremely interesting topic of MHE treatment in adults. The video is available with subtitles in Polish.

See other entries

October 15, 2026
How to Properly Care for a Stump After Amputation? A Practical Guide
Stump care following amputation is an important part of regaining mobility, preparing for prosthetic fitting, and preventing skin and functional complications. Proper hygiene, daily skin monitoring, edema management, correct limb positioning, and rehabilitation help create the conditions for proper healing and continued improvement. However, the course of treatment depends on the level of amputation, the reason for the procedure, the condition of the wound, and the treatment method used. […]
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Hollow Foot – Symptoms, Causes, and Treatment Options
A high arch (pes cavus) is a deformity in which the longitudinal arch of the foot is excessively arched. The mere presence of a high arch does not always indicate a medical condition—for some people, it is simply a variation in foot structure that causes no symptoms. The problem arises when the increased arch is associated with abnormal weight distribution, pain, ankle instability, toe deformity, or […]
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Aplasia—What Is It, and What Are Its Causes?
Aplasia is a developmental disorder in which a specific tissue, structure, or organ does not develop properly or does not reach full maturity. In orthopedics, this term may refer, among other things, to the underdevelopment or absence of a portion of a bone, a limb, a segment of a limb, or specific structures of the musculoskeletal system. The extent of the abnormalities varies widely—from minor underdevelopment of a single […]